Ecological Complexity Lab Elucidating the complexity of ecological systems

Our new research, "Metabolite correlation networks reveal complex phenotypes of adaptation-driving mutations", is now available on Nature Communications!

The study, previously available as a preprint, is now published following peer-review in Nature Communications!

In this study, as part of a collaboration with Shimon Bershtein’s lab, we show that adaptive evolution can reshape the structure of metabolic networks, creating complex phenotypes that link mutations to fitness. Using a metabolically impaired E. coli strain, the team demonstrates that fitness gains arise from large-scale rewiring of metabolite correlation networks, producing smaller, more cohesive, and better-connected clusters. These results highlight metabolite correlation networks as a powerful framework for uncovering emergent phenotypes that drive metabolic adaptation.

Read the full paper here: Nature Communications

figure image
Previous post
Our new research, "Contextual evidence for categorising interactions and guiding their discovery", is now available on EcoEvoRxiv!
Next post
Our new research, "Disentangling the drivers of parasite occurrence in a native and a non-native small mammal across a land-use gradient", is now available on EcoEvoRxiv!